Research highlights how GLP-1 receptor agonists may improve brain health by targeting the neurovascular unit, linking metabolic health to cognitive function. It suggests potential therapies for neurodegenerative diseases like Alzheimer's.

Study reveals the drug, 5-fluorouracil, acts differently in different types of cancer — a finding that could help researchers design better drug combinations.

Researchers developed novel genetic tools to trace, ablate, and manipulate p16^Ink4a+^ senescent cells, revealing their distinct roles in liver fibrosis and repair. Senescent macrophages promote fibrosis, while endothelial cells aid in tissue recovery.

Imagine a world where your own immune cells are transformed into cancer-fighting superheroes.

Multiple myeloma is a type of blood cancer that appears mainly after the age of sixty. Its incidence, therefore, increases with the aging of the population.

CDK12 is established as a tumor suppressor in prostate cancer, with its loss driving aggressive disease and creating vulnerabilities for targeted therapies.

"These findings offer a future where recharging our cells becomes possible, extending healthy lifespans..."

Doctors have long believed the cancer drug 5-fluorouracil works by damaging the building blocks of DNA, but researchers have now found that in certain cancers, it kills cells by interfering with RNA synthesis. The findings could help researchers design better drug combinations for colon and gastrointestinal cancers.