Study identifies key inflammatory and immune response proteins linked to endometrial cancer risk through both observational and Mendelian Randomization analyses, revealing the roles of IL-6 and HSD11B1.

Acute Myeloid Leukemia (AML) remains one of the most challenging hematological malignancies to treat, with relapse and refractory cases continuing to pose significant hurdles

This study reveals hepcidin's significant role in psoriasis, linking iron retention to inflammation and keratinocyte growth, suggesting new therapeutic targets.

Researchers discovered microplastics in both tumor and para-tumor prostate tissues, with higher concentrations found in tumor samples, raising concerns about their potential role in cancer development.

Researchers in China found multiple types of microplastics in human semen and urine, with exposure to PTFE significantly linked to reduced sperm quality, highlighting potential reproductive health risks.

Penn Medicine researchers will advance their understanding of the underlying causes of cognitive decline in individuals with Lewy body diseases, like Parkinson's, and identify biomarkers that predict which individuals are more likely to develop dementia with a $18 million grant from the National Institutes of Health/National Institute on Aging.

SAINT-PREX, Switzerland — Ferring Pharmaceuticals today announces results from the OPTIMISE study showing the first real-world evidence of the effectiveness of a treat-to-target (T2T) approach based on faecal calprotectin (FC) in patients with mild-to-moderate ulcerative colitis (M2M UC). These results have been published in the Journal of Clinical Medicine.1

A blood test that uses artificial intelligence (AI) to detect cancer-related genetic changes and protein biomarkers could help screen women for early signs of ovarian cancer, according to a study by researchers at the Johns Hopkins Kimmel Cancer Center in collaboration with several other institutions in the United States and Europe.

The study finds a significant correlation between premature ovarian insufficiency and autoimmune diseases, urging further investigation into prevention methods.

Research has revealed how disruption of the circadian clock, the body's internal, 24-hour biological pacemaker, may accelerate the progression of colorectal cancer by affecting the gut microbiome and intestinal barrier function. This discovery offers new avenues for prevention and treatment strategies.

Review highlights how gut dysbiosis and dietary factors are linked to rheumatoid arthritis, influencing disease progression and inflammation. Researchers explore how specific diets may help modulate the gut microbiome to improve symptoms.

People with limited-stage small cell lung cancer may benefit from adding immunotherapy to chemoradiation, but not if both treatments are given at the same time, new research finds.

Researchers find that ultra-processed food (UPF) consumption may not be directly responsible for poor health outcomes, with lifestyle factors playing a significant role. More experimental research is needed to establish causality.

Research indicates phytoene from microalgae protects against oxidative stress and beta-amyloid toxicity, suggesting its potential in promoting healthy aging.

An accelerated course of radiation therapy does not increase complications for patients who undergo breast reconstruction following a mastectomy, new research shows.

Researchers looking to de-intensify radiation treatments for people with early-stage, HPV-associated oropharyngeal cancer to prevent long-term side effects halted a large, randomized phase II/III trial after patients in the control arm reached a record high, two-year progression-free survival rate of 98%.

With a four-year, $3.3 million grant from the National Institutes of Health (NIH), researchers from Case Western Reserve University will study whether certain brain proteins may play a role in the development of Alzheimer's disease.

People with low- and intermediate-risk prostate cancer treated with either of two types of contemporary radiation therapy -; proton beam therapy or intensity modulated radiation therapy (IMRT) -; achieved equally high rates of tumor control with no differences in patient-reported quality of life, according to a first-of-its-kind phase III clinical trial comparing the two technologies. Findings of the PARTIQoL trial will be presented today at the American Society for Radiation Oncology (ASTRO) Annual Meeting.

Research indicates that high flavonoid intake is linked to a lower risk of NAFLD, with apples and tea showing significant protective effects on liver health.

Weill Cornell Medicine investigators have found that two genetic variants that confer high risk of Alzheimer's disease (AD) together trigger a harmful inflammatory response in the brain's immune cells, particularly in females, in a preclinical model.