Type 2 diabetes patients may benefit from reduced carbohydrate intake
· News-MedicalThe researchers gathered data from 57 white and Black adults with type 2 diabetes, half on a low-carbohydrate diet and the other half on a high-carbohydrate diet and examined their beta-cell function and insulin secretion at baseline and after 12 weeks.
All of the participants' meals were provided. People on the carbohydrate-restricted diet ate 9% carbohydrates and 65% fat, and participants on the high-carbohydrate diet ate 55% carbohydrates and 20% fat.
The researchers found those on a low-carbohydrate versus a high-carbohydrate diet saw improvements in the acute and maximal beta-cell responses that were 2-fold and 22% greater, respectively. Within each race group, Black adults on a low-carbohydrate diet saw 110% greater improvements in the acute beta-cell response and White adults had improvements in the maximal beta-cell response that were 48% greater than their respective counterparts on the high-carbohydrate diet.
"Further research is needed to determine if a low-carbohydrate diet can restore beta-cell function and lead to remission in people with type 2 diabetes," Gower said.
Other study authors include Amy Goss, Marian Yurchishin and William Garvey of the University of Alabama at Birmingham; Sarah Deemer of the University of North Texas in Denton, Texas; and Bhuvana Sunil of the University of Washington and Mary Bridge Children's Hospital in Tacoma, Wash.
This research received financial support from the National Institute of Diabetes and Digestive and Kidney Diseases, the Nutrition Obesity Research Center of the University of Alabama at Birmingham, the Diabetes Research Center, and the National Heart, Lung, and Blood Institute.
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