49ers vs. Seahawks NFL props, AI prediction, Thursday Night Football picks: Jordan Mason over 81.5 yards

Thursday Night Football prop picks for San Francisco vs. Seattle for sites like PrizePicks, Underdog Fantasy, DraftKings, Pick6, and more

A classic NFC West rivalry will resume on Thursday Night Football as the San Francisco 49ers visit the Seattle Seahawks. Familiar names like George Kittle, Deebo Samuel, DK Metcalf and Tyler Lockett will populate plenty of NFL prop bets, but there are other players who have made their presences felt for these teams. 49ers running back Jordan Mason has has filled in admirably for Christian McCaffrey, while Jaxon Smith-Njigba is showing why he was a first-round pick. Thus, you'll have no shortage of quality NFL player props to choose from for Seahawks vs. 49ers picks.

Smith-Njigba has a receiving yardage bar at 49.5, and he's averaging 51.4 this season. However, he had fewer than 45 receiving yards in both games versus San Francisco last year and has gone Under 49.5 in five of his last seven games overall. The second-year wideout ranks third on Seattle in yards, but leads the team in receptions, so his receptions NFL prop could be the one to focus on. Before betting any NFL props for Thursday Night Football or entering NFL predictions on sites like PrizePicks, you need to see the Seahawks vs. 49ers NFL prop predictions powered by SportsLine's AI PickBot.

Built using cutting-edge artificial intelligence and machine learning techniques by SportsLine's Data Science team, AI Predictions and AI Ratings are generated for each player prop. The AI predictions are determined by statistically learning from each player's historical data and then quantitatively evaluating the strength of the opponent's defense by assigning a numeric value out of 100 called a matchup score. 

Once a prediction is formulated, the AI rating is generated using the prediction, the matchup score, and the odds of the market. Last season, the AI PickBot hit a whopping 1,674 4.5- and 5-star prop picks. This year, it has already nailed 128 picks rated 4 stars or better. Anybody who followed those picks was way up.

For 49ers vs. Seahawks NFL betting on Thursday Night Football, the AI PickBot has evaluated the NFL player prop odds and provided Seahawks vs. 49ers prop picks for every available prop market. You can only see the AI player prop predictions for Seattle vs. San Francisco here.

Top NFL player prop bets for 49ers vs. Seahawks

After analyzing Seahawks vs. 49ers props and examining the dozens of NFL player prop markets, the AI PickBot says 49ers running back Jordan Mason goes Over 81.5 rushing yards. The NFL's second-leading rusher is averaging 107.2 rushing yards per game, which is 16 more than Christian McCaffrey averaged last season en route to winning the Offensive Player of the Year award. Mason is coming off 89 yards against the Cardinals and has gone over 81.5 rushing yards in four of his five games this season.

The Seahawks were just gashed on the ground by another backup running back, rookie Tyrone Tracy Jr. of the Giants. The fifth-round pick ran for 129 yards on just 18 carries, averaging 7.2 yards per rush. Mason can expect more than 18 carries since he leads the NFL with 105 rushing attempts. That volume has the AI model projecting that Mason finishes with 97.8 rushing yards in a prop pick with a 4-star rating. See more NFL props here.

How to make NFL player prop bets for San Francisco vs. Seattle

In addition, the AI PickBot says another star sails past his total and has five other NFL props rated 4 stars or better. You need to see the AI PickBot's analysis before making any 49ers vs. Seahawks prop bets for Thursday Night Football.

Which Seahawks vs. 49ers prop bets should you target for Thursday Night Football? Visit SportsLine now to see the top 49ers vs. Seahawks props, all from the SportsLine AI PickBot that nailed 1,674 top-rated picks last season and has hit 128 picks this year.