Monday Night Football prediction, odds, line, time, spread: Seahawks vs. Lions picks by expert on 25-11 roll

SportsLine's Josh Nagel just revealed his Detroit Lions vs. Seattle Seahawks picks for Monday Night Football

The Detroit Lions will try to snap a six-game series losing streak to the Seattle Seahawks when they meet in a Monday Night Football showdown at Ford Field in Detroit. Both teams are coming off wins after Seattle downed Miami, 24-3, and Detroit stopped Arizona, 20-13. The Seahawks (3-0), who are off to their best start since 2020 when they went 5-0 out of the gate, are 5-5 on the road since the start of last season. The Lions (2-1), who are looking to win the NFC North for the second year in a row, are 7-3 on their home field since the beginning of 2023. 

Kickoff from Ford Field in Detroit is set for 8:15 p.m. ET. Detroit is a four-point favorite in the latest Seahawks vs. Lions odds after the line opened at -6, while the over-under for total points scored is 47. Before you make any Seahawks vs. Lions picks or predictions, make sure you check out what SportsLine NFL expert Josh Nagel has to say, considering his mastery of picks involving the Seahawks.

Nagel is a Reno-based analyst and radio host who has worked in the sports handicapping industry for more than 20 years. SportsLine's assistant managing editor has covered the wagering industry on a variety of platforms, and has won numerous sports handicapping contests. In addition, Nagel has gone 25-11 on his last 36 picks involving the Seahawks, returning $1,345. Anyone who has followed him is way up.

Now, Nagel has zoned in on Seahawks vs. Lions. You can head to SportsLine to see his picks. Here are the NFL odds and NFL betting lines on the spread, money line and over/under for Lions vs. Seahawks:

• Seahawks vs. Lions spread: Detroit -4
• Seahawks vs. Lions over/under: 47 points
• Seahawks vs. Lions money line: Seattle +177, Detroit -213
• SEA: Seahawks have hit the first-quarter money line in five of their last 11 away games (+5.65 units)
• DET: Lions have covered the spread in 16 of their last 21 games (+10.50 units)  
• Seahawks vs. Lions picks: See picks at SportsLine

Why the Lions can cover

Quarterback Jared Goff had two touchdown passes and a 113.6 rating last week. He has 275-plus passing yards in four of his past five games at home. Goff has 3,107 pass yards (282.5 per game) in 11 career regular season games against Seattle, including 300 or more passing yards in six games. He will be looking for his third game in a row vs. Seattle with 300 or more passing yards, three-plus TD passes and a 120-plus rating.

Running back Jahmyr Gibbs had 103 yards from scrimmage yards (83 rushing and 20 receiving) and his second career receiving touchdown in last week's win over the Cardinals. He will be looking for his third game in a row with 100-plus scrimmage yards. For the season, Gibbs has carried 40 times for 207 yards (5.2 average) and one touchdown. He has two explosive plays of 20 or more yards, including a long of 24. See who to back at SportsLine. 

Why the Seahawks can cover

Eleven-year veteran quarterback Geno Smith continues to produce. In three games this season, he has completed 77 of 103 passes (74.8%) for 787 yards and three touchdowns. He has been picked off three times, but has a rating of 93.8. He has also rushed 11 times for 36 yards, including a long of 34 yards, and a score. In last Sunday's win over Miami, he completed 26 of 34 attempts (76.5%) for 289 yards and one touchdown with two interceptions.

His favorite target has been sixth-year veteran wide receiver DK Metcalf. He has caught 17 passes for 262 yards (15.4 average) and two touchdowns. He has three explosive plays of 20 yards or more, including a season-high 71 yarder. He has also registered 105 yards after the catch and has converted seven first downs. In the 23-20 overtime win over the New England Patriots in Week 2, he caught 10 passes for 129 yards and a score. See who to back at SportsLine. 

How to make Seahawks vs. Lions picks

Nagel has analyzed Seahawks vs. Lions from every possible angle, and while we can tell you he's leaning Over the point total, he has also discovered a critical X-factor that has him jumping all over one side of the spread. Head to SportsLine to see what it is, and find out which team to back.

Who wins Seahawks vs. Lions on MNF, and which critical x-factor makes one side of the spread hit hard? Visit SportsLine now to see which side of the Lions vs. Seahawks spread you need to jump on, all from the expert who returned more than $1,300 to $100 players in the last 36 picks involving the Seahawks, and find out.