Self-learning AI gives NFL against the spread, over-under, money-line picks for every Week 4, 2024 game

SportsLine AI evaluated the Week 4 NFL odds and revealed its NFL predictions, NFL score predictions, and NFL betting picks for every game

The NFC South is shaping up to be one of the most competitive divisions this season, as the Saints, Buccaneers and Falcons look like title-contenders through the first three weeks of the season. New Orleans and Atlanta will meet on Sunday during the Week 4 NFL schedule, as the Saints try to bounce back from their first loss of the campaign. They are 2.5-point underdogs in the Week 4 NFL odds, with the Falcons coming off a narrow loss to Kansas City. Should you back either team with your Week 4 NFL best bets?

Tampa Bay is a 1.5-point home underdog against Philadelphia in the NFL spreads after getting blown out at home by Denver in a surprising result last week. The Eagles are going on the road for the second straight week following a 15-12 win at New Orleans last week. Before you make any Week 4 NFL picks, you need to see the NFL against the spread, over-under, and money line predictions powered by the self-learning SportsLine AI.

Built using cutting-edge artificial intelligence and machine learning techniques by SportsLine's Data Science team, AI Predictions and AI Ratings are generated for each game. The AI predictions are determined by statistically learning from each team's historical data and then quantitatively evaluating the strength of the opponent's defense by assigning a numeric value out of 100 called a matchup score. 

Once a prediction is formulated, the AI rating is generated using the prediction, the matchup score, and the odds of the market. For example, you could see an A-rating on an over bet if a team is facing a poor defense, their prediction differs from the line and there are favorable odds.

In addition, SportsLine AI is the first fully automated predictive model at SportsLine. It continuously refreshes on the most recent available data and can help you spot the biggest discrepancies in the lines. Last season, SportsLine's AI PickBot hit a whopping 1,674 4.5- and 5-star prop picks. Anyone who has followed it is way up.

For Week 4 NFL betting, the AI PickBot has evaluated the NFL odds and provided NFL betting predictions for all 16 games. You can only see the AI predictions for the Week 4 NFL schedule here.

Top Week 4 NFL AI picks

After analyzing every game in Week 4, the AI PickBot says the Jaguars cover as 6-point road underdogs against the Texans. Houston was just a 4-point favorite in the look-ahead line for this game prior to suffering a blowout loss to Minnesota last week, but the line still jumped multiple points after Jacksonville dropped to 0-3. The Jaguars now head into this game in desperation mode, especially since this is their first divisional game of the season.

Quarterback Trevor Lawrence was successful in his last trip to Houston, picking up a 24-21 win against the Texans last November. Texans quarterback C.J. Stroud threw his first two interceptions of the season last week, and his team has committed 23 combined penalties over their last two games. This is a nice spot to fade Houston at an inflated number, as the AI PickBot has the Texans winning by just two points on average. See its other Week 4 football predictions and football picks at SportsLine.

How to make Week 4 NFL picks

In addition, the AI PickBot has generated 11 other A-rated picks for Week 4. You need to see the AI PickBot's picks before making any Week 4 NFL bets of your own. You can only see them at SportsLine.

Who wins and covers each Week 4 NFL game, and which A-rated picks should you target?  Visit SportsLine now to see the top NFL picks against the spread, over-under, and on money line, all from the brand-new SportsLine AI PickBot that nailed 1,674 top-rated picks last season.