Oklahoma vs. Tennessee prediction, odds, line: 2024 college football picks, Week 4 bets by proven computer

SportsLine's model just revealed its Week 4 college football picks and predictions for Tennessee Volunteers vs. Oklahoma Sooners on Saturday

The No. 15 Oklahoma Sooners (3-0) will make their SEC debut in primetime on Saturday night when they host the No. 6 Tennessee Volunteers (3-0). Oklahoma is wrapping up a four-game season-opening homestand with its first-ever conference game as a member of the SEC. Tennessee has scored more than 50 points in all three of its wins to open the season, including a modern-era school-record 71 points in its win over Kent State last week. The Vols are in their fourth season under head coach Josh Heupel, who led Oklahoma to a national championship as a quarterback in 2000, finishing as the runner-up in the Heisman Trophy voting.

Kickoff is set for 7:30 p.m. ET at Gaylord Family-Oklahoma Memorial Stadium in Norman. The Vols are 6.5-point favorites, per SportsLine consensus, in the latest Oklahoma vs. Tennessee odds. The over/under for total points is 56.5, down from opening at 61.5. Before making any Tennessee vs. Oklahoma picks, be sure to check out the college football predictions and betting advice from the SportsLine Projection Model.

The model simulates every FBS college football game 10,000 times. Since its inception, it has generated a profit of well over $2,000 for $100 players on its top-rated college football picks against the spread. It is also coming off a profitable 13-9 season on top-rated spread picks and is off to a 5-2 start on over/under picks this season. Anyone who has followed it has seen strong returns.

Now, the model has set its sights on Oklahoma vs. Tennessee and just locked in its picks and CFB predictions. You can visit SportsLine now to see the model's picks. Here are the college football odds and betting lines on the spread, money line and over/under for Tennessee vs. Oklahoma:

• Oklahoma vs. Tennessee spread: Tennessee -6.5
• Oklahoma vs. Tennessee over/under: 56.5 points
• Oklahoma vs. Tennessee money line: Tennessee -254, Oklahoma +204
• OU: The Sooners are 6-2 ATS in their last eight against SEC opponents 
• UT: The Volunteers have covered in four of their last five 
• Oklahoma vs. Tennessee picks: See picks at SportsLine

Why Oklahoma can cover

The Sooners have started out 3-0 in each of Brent Venables' three seasons at the helm, but lost six of 10 in 2022 and then lost three of six last season to finish at 10-3 after a 7-0 start. Sophomore quarterback Jackson Arnold has accounted for nine touchdowns so far this season, but he's averaged just 5.6 yards per pass attempt this year and the Sooners have averaged only 325.3 yards of total offense per game.

However, the Oklahoma defense has looked like one of the most opportunistic units in the nation early in the year. Led by linebacker Danny Stutsman, the Sooners have forced 10 turnovers already this season with 10 sacks and 22 tackles for loss. Look for Venables to use his defensive playmakers to throw some complex looks at Nico Iamaleava in his fifth career start and for the crowd noise to be a factor in Iamaleava's first career road start. See which team to pick here. 

Why Tennessee can cover 

While both teams are unbeaten through their first three games, Tennessee has been significantly more impressive. The Vols blew out Chattanooga, NC State and Kent State by a combined score of 191-13, ranking first in points scored and allowed per drive. Quarterback Nico Iamaleava has completed 71.6% of his passes, averaging nearly 10 yards per dropback.

Oklahoma has won its past two games by just 19 total points, despite having an even weaker strength of schedule. Quarterback Jackson Arnold ranks outside the top 120 nationally per dropback, and he has already been sacked nine times. He is facing a Tennessee defense that is led by star edge rusher James Pearce Jr., who had 10 sacks last season. See which team to pick here. 

How to make Oklahoma vs. Tennessee picks

SportsLine's model is leaning Over on the total, projecting 63 combined points. The model also says one side of the spread hits well well over 50% of the time. You can only get the model's pick at SportsLine. 

So who wins Tennessee vs. Oklahoma, and which side of the spread hits in well over 50% of simulations? Visit SportsLine now to see which side of the spread to jump on, all from the advanced computer model that's up well over $2,000 on its college football picks since inception, and find out.