Oregon vs. Michigan odds, betting line: 2024 college football picks, Week 10 predictions by proven model

SportsLine's model revealed its CFB picks and predictions for Michigan Wolverines vs. Oregon Ducks on CBS and Paramount+

A new Big Ten rivalry begins when the Michigan Wolverines (5-3) host the top-ranked Oregon Ducks (8-0) Saturday on CBS and Paramount+. These teams met as non-conference foes five times, with Oregon winning the last matchup 39-7 in Ann Arbor in 2007. The Ducks have built on their crucial Week 7 win over Ohio State, winning and covering against Purdue and Illinois in the past two weeks. Michigan, meanwhile, snapped a two-game losing streak by beating rival Michigan State 24-17 in Week 9, covering as 3-point favorites in that one. 

Kickoff from Michigan Stadium is set for 3:30 p.m. ET. The Ducks are 15.5-point favorites in the latest Oregon vs. Michigan odds via SportsLine consensus. The over/under is 45.5. Before making any Michigan vs. Oregon picks, be sure to check out the college football predictions and betting advice from the SportsLine Projection Model.

Saturday's game can be seen live on CBS and streamed live on Paramount+, which you can now get for a 7-day free trial. Sign up right here.

The model simulates every FBS college football game 10,000 times. Since its inception, it has generated a profit of well over $2,000 for $100 players on its top-rated college football picks against the spread. It's also on a 16-7 run on top-rated college football picks over the past five weeks. Anyone who has followed it has seen strong returns at sportsbooks and sports betting apps. 

Now, the model has dialed in on Oregon vs. Michigan and just revealed its coveted betting picks and predictions. You can head to SportsLine now to see the model's picks. Here are the college football odds for the Michigan vs. Oregon matchup:

• Oregon vs. Michigan spread: Oregon -15.5
• Oregon vs. Michigan over/under: 45.5 points 
• Oregon vs. Michigan money line: Oregon -725, Michigan +510
• Oregon vs. Michigan picks: See picks at SportsLine
• Oregon vs. Michigan streaming: Paramount+ (Get 7 days free)

Why Oregon can cover

The Ducks have now rolled to a 5-0 start in Big Ten play, including that massive win over Ohio State in Week 7, a shutout at Purdue in Week 8 and a 38-9 blowout of Illinois in Week 9. They've now covered the spread in three straight and four of their last six after beginning the year 0-2 ATS. Oregon has talent all over the field, but it is particularly stacked at the skill positions.

Receivers Tez Johnson (638 yards, 8 TDs) and Evan Stewart (446 yards, 3 TDs) make up one of the best duos in the nation. Running back Jordan James has an impressive 136-800-8 rushing line. Quarterback Dillon Gabriel has been extremely efficient, completing 76.2% of passes for 2,371 yards, 18 touchdowns and just five interceptions. Michigan, meanwhile, ranks near the bottom of the Big Ten in total and scoring offense and doesn't appear to be built to keep up in this one. See picks at SportsLine.

Why Michigan can cover

The Wolverines hope they've found something at quarterback in Davis Warren, who performed well against Michigan State. Warren won the starting job out of camp before giving it up and then earning it back again in Week 9. He completed 13-of-19 passes for 123 yards, a touchdown and no interceptions against the Spartans. 

The running back duo of Kalel Mullings (123-694-7) and Donovan Edwards (89-415-3) should pose some issues for an Oregon rush defense that ranks 11th in the Big Ten. Only one opponent -- then-No. 3 Texas -- has surpassed 30 points against Michigan, so the Wolverines will be tough to blow out at home. See picks at SportsLine.

How to make Illinois vs. Michigan picks

SportsLine's model is going Over on the total, projecting 54 combined points. It also says one side of the spread hits in over 60% of simulations. You can see the model's pick at SportsLine.

So who wins Michigan vs. Oregon, and which side of the spread hits over 60% of the time? Visit SportsLine now to see which side of the spread to jump on, all from the advanced model that is up well over $2,000 on top-rated spread picks since its inception, and find out, and don't forget to stream the game on Paramount+.