Boston College vs. Louisville prediction, odds, spread: 2024 college football picks, prop bets from top expert

SportsLine's Jimmie Kaylor revealed his Week 9 CFB picks, ACC predictions and props for the Boston College Eagles vs. Louisville Cardinals game on Friday

The Louisville Cardinals (4-3, 2-2) look to move one step closer to bowl eligibility when they travel to Chestnut Hill, Mass., to take on the Boston College Eagles (4-3, 1-2) on Friday. Louisville is 1-1 on the road, while Boston College is 3-0 at home. The Cardinals are looking to bounce back from a 52-45 loss to Miami in one of the highest-scoring games of the season. The Eagles are looking to snap a two-game losing streak after falling to Virginia Tech 42-21 on Oct. 17. Both teams are 4-3 against the spread in 2024.

Kickoff at Alumni Stadium is scheduled for 7:30 p.m. ET. The Cardinals are favored by 7.5 points in the latest Boston College vs. Louisville odds via SportsLine consensus, while the over/under is 53.5 points. Before making any Louisville vs. Boston College picks, you need to see the Week 9 college football predictions and betting advice from SportsLine's Jimmie Kaylor. 

Kaylor is an NFL, college football and DFS expert for SportsLine, who has covered the NFL and college football for close to a decade as a member of the Pro Football Writers of America. His background as a former college football All-American and NFL player gives him a unique perspective when building his fantasy lineups and locking in his betting picks. He has his finger on the pulse of the college football landscape and has been cashing in big on sports betting apps for the last two years. 

Kaylor has destroyed the sportsbooks in college football the last two seasons, netting a whopping 63.8 units while posting a 178-107-2 record since Week 1 of the 2023 season. All of his picks have been featured on his SportsLine expert page or in his weekly bylined articles. Anyone who followed his picks is way up.

Now, Kaylor has dialed in on Boston College vs. Louisville on Friday and just revealed his college football picks and predictions. You can head to SportsLine now to see his picks. Here are the college football odds and betting lines for Louisville vs. Boston College:

• Louisville vs. Boston College spread: Louisville -7.5
• Louisville vs. Boston College over/under: 53.5 points 
• Louisville vs. Boston College money line: Louisville -146, Boston College +121
• Louisville vs. Boston College picks: See picks at SportsLine
• Louisville vs. Boston College streaming: FuboTV (Try for free)

Why Louisville can cover

Prior to its loss to Miami, Louisville had ranked as one of the top defensive teams in the ACC. The Cardinals allowed 538 total yards and 45 offensive points (Miami also scored a fumble return touchdown) to the Hurricanes, which looks like more of an outlier performance than a true indication of what they can do defensively. Louisville currently is averaging 364.9 total yards allowed and 24.3 points per game. 

On the offensive side of the ball, quarterback Tyler Shough has been outstanding in his first season with the program. The former Oregon and Texas Tech signal caller has thrown for 2,016 yards, 18 touchdowns and three interceptions. His top target has been wide receiver Ja'Corey Brooks, who has 36 catches for 679 yards and eight touchdowns. See which team to pick here. 

Why Boston College can cover

Boston College has a perfect 3-0 record at home this season. Head coach Bill O'Brien is highly experienced at both the college and NFL levels, and has helped turn Boston College into one of the most physical teams in the ACC in his first season on the job. O'Brien is no stranger to coaching successful football teams in the Boston area having spent six seasons on Bill Belichick's New England Patriots staff. 

The Eagles have one of the most dynamic players in the conference in Thomas Castellanos. The 5-foot-9 junior is a dual-threat quarterback, who has the ability to single-handedly take over games with his improvisation skills. Castellanos enters this matchup with 1,118 passing yards, 14 touchdown passes, four interceptions, 161 rushing yards and one score. See which team to pick here. 

How to make Boston College vs. Louisville picks

Kaylor has analyzed Louisville vs. Boston College from every angle and he's leaning Under on the point total. He has also discovered a critical X-factor that has him jumping all over one side of the spread. He's only sharing what it is, and which side to back, at SportsLine.

So who wins Louisville vs. Boston College on Friday, and what critical X-factor makes one side of the spread a must back? Visit SportsLine now to see which side of the spread to jump on, all from the expert who has profited $6,380 for $100 college football bettors since Week 1 of 2023 season, and find out.